A Non-interventional, Epidemiological, Registry-based Evaluation of Anaemia in Swedish Patients With Chronic Kidney Disease (ASK)

Astellas

Status: Completed

Conditions: Chronic Kidney Disease Associated Anemia

Treatments: Other: Non-Interventional

Study type: Observational

Funder types: Industry

Identifiers

NCT03643601

1517-MA-3139-SN

Details and patient eligibility

About

The primary purpose of this study is to describe renal anemia treatment patterns in non-dialysis dependent (ND) and dialysis dependent (DD) populations, with a particular focus on iron use in erythropoiesis stimulating agent (ESA) treated patients.

This study will also provide an epidemiological description of chronic kidney disease (CKD) associated anemia in relation to CKD stage, dialysis modality and underlying morbidity, as well as describe the relationship between inflammation and ESA treatment and describe the associated cardiovascular illness in ESA treated patients.

Full description

Data from year 2015 will be used for the prevalence analysis.The prevalent population of CKD patients > 18 years in the Swedish Renal Registry in 2015 both dependent on dialysis (DD) and not on dialysis (ND).

Enrollment: 14,415 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• For ND-CKD population:

  • all prevalent patients with a CKD with Estimated Glomerular filtration rate (eGFR) < 45ml/min/1.73m2 with a recorded visit pre-dialysis in Swedish Renal Registry (SRR) in 2015
  • Not on dialysis

• For DD-CKD population

  • All prevalent patients taking part in the yearly cross-sectional dialysis investigation in SRR in 2015
  • Dialysis dependent

Exclusion criteria

• not applicable

Trial design

14,415 participants in 2 patient groups

Non-Dialysis (ND) Patients

Description:

For the ND patients, data are captured on each clinic visit during the course of the year (2-4 times per year), the last available record for 2015 will be used.

Treatment:

Other: Non-Interventional

Dialysis (DD) Patients

Description:

For the DD patients, data are input from a randomly selected visit to the hospital in September to October 2015; the evaluation will be based on this record.

Treatment:

Other: Non-Interventional