A Novel Neurobehavioral Intervention for Emotion Regulation in Anxiety and Depression Across the Lifespan

Stanford University

Status: Completed

Conditions: Depression, Anxiety; Cognitive Training; Emotion Training; Emotion Regulation

Treatments: Behavioral: Computerized neurobehavioral intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT01616797

IRB-24813

Details and patient eligibility

About

The research proposes to use an innovative solution to shape brain circuits that support executive function and emotion reactivity -using targeted neurobehavioral intervention.

Full description

Participants will be recruited locally in the San Francisco Bay area with certain symptoms of anxiety and depression. They will complete a clinical assessment and then take part in a cognitive-emotion training delivered online.

Enrollment: 68 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of depression on the SCID, a total Ham-D≥16 and Ham-D anxiety/somatization subscale ≥ 7.

Exclusion criteria

• Current medication for psychiatric disorders
• Pregnant females
• Head trauma or injury that resulted in loss of consciousness
• MRI contraindication

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

---

68 participants in 2 patient groups

Computerized intervention

Experimental group

Description:

Participants will be asked to visit a customized website and engage in computerized exercises. Cognitive and emotion training games.

Treatment:

Behavioral: Computerized neurobehavioral intervention

Control

Sham Comparator group

Description:

Participants will be asked to visit a customized website and engage in computerized games.

Treatment:

Behavioral: Computerized neurobehavioral intervention