A Novel Serological Risk Model for Early Non-invasive Diagnosis of Cholangiocarcinoma

Sun Yat-sen University

Status

Not yet enrolling

Conditions

Cholangiocarcinoma

Treatments

Diagnostic Test: No interventions

Study type

Observational

Funder types

Other

Identifiers

NCT06658587

SYSKY-2024-352-01

Details and patient eligibility

About

This is a prospective, observational and exploratory clinical study. The object of this study is to evaluate the accuracy of a novel serological risk model on blood samples in early diagnosis of cholangiocarcinoma patients.

Full description

A reliable and accurate preoperative tool capable of early diagnosing malignant cholangiocarcinoma is lacking and urgently needed for clinical practice. This study proposes to establish and evaluate a novel serological risk model on blood samples for non-invasively diagnosing cholangiocarcinoma. The study includes the construction of capable novel serological risk model and the validation of the diagnosis model.

Enrollment

60 estimated patients

Sex

All

Ages

18 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

1. The patient must sign an informed consent form;
1. Age 18-75 years old, both male and female;
1. ECOG performance status score (PS score) 0-2;
1. Cholangiocarcinoma with resectable tumor lesions;
1. Complete the blood collection before treatment;

Exclusion criteria

1. Accompanied with other primary malignant tumors;
1. Patients who have neoadjuvant chemotherapy or other tumor-targeted therapies;
1. Incomplete serological examinations or medical history data.