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A Novel Surgical Strategy to Reduce Major Complications in Patients With Necrotizing Pancreatitis

T

Tianjin Nankai Hospital

Status

Completed

Conditions

Acute Pancreatitis

Treatments

Procedure: The novel PMMI surgical strategy
Procedure: The conventional step-up strategy

Study type

Observational

Funder types

Other

Identifiers

NCT06241586
TianjinNH

Details and patient eligibility

About

The goal of this observational study is to compare patient outcomes between the groups of patients admitted before and after the full implementation of the novel surgical strategy in patients with necrotizing pancreatitis. The main question it aims to answer are:

• the efficacy and safety of the novel surgical strategy To assess the efficacy and safety of the novel surgical strategy, all included patients were divided into two groups according to the timing of receiving treatment: 1) the early period group: patients admitted before January 2021 received the hybrid strategy of traditional and novel surgical strategies; and 2) the late period group: patients admitted during and after January 2021 received the complete novel surgical strategy.

Enrollment

271 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Consecutive patients older than 18 years with necrotizing pancreatitis were included.

Exclusion criteria

Patients who met one or more of the following criteria were excluded: (1) had a past medical history of acute pancreatitis; (2) had drainage or surgery for pancreatic necrosis in other hospitals before admission to our institute; and (3) did not complete the treatment strategy owing to nonmedical reasons.

Trial design

271 participants in 2 patient groups

the early period group
Description:
Patients admitted before January 2021 received the hybrid strategy of traditional and novel surgical strategies.
Treatment:
Procedure: The conventional step-up strategy
Procedure: The novel PMMI surgical strategy
the late period group
Description:
Patients admitted during and after January 2021 received the complete novel PMMI surgical strategy.
Treatment:
Procedure: The novel PMMI surgical strategy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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