A Perianal Abscess Cavity Packing vs no Packing.

Dow University of Health Sciences

Status: Completed

Conditions: Perianal Abscess; Ischiorectal Abscess

Treatments: Procedure: No packing of perianal abscess cavity

Study type: Interventional

Funder types: Other

Identifiers

NCT04832529

IRB-1537/DUHS/Approval/2020

Details and patient eligibility

About

This prospective randomized trial will be conducted in all patients undergoing packing or no packing for perianal abscess cavity after incision and drainage, for 6 months after approval from IRB in Surgical unit III, Civil Hospital Karachi. Patient will be selected simple random sampling technique based on inclusion criteria. Patient will be assessed for post-operative pain, healing of cavity and recurrence of abscess. At first time of debridement pus or tissue will be sent for culture and sensitivity, meanwhile broad-spectrum antibiotic will be started.

Questionnaire will be filled by PI for post-operative pain, recurrence of abscess, quality of life, wound healing, post operative fistula in ano and chronic post surgical pain either due to packing or no packing.

Full description

This is an experimental randomized control trial will start 6 months after approval from Institution Review Board. All patients with perianal abscess after incision and drainage cavity will be either packed or not after informed consent. Pack will be changed daily as regular dressing till healing occurs. Packing reduces bleeding and heals cavity by effect of dressing solution in which gauze is soaked. Other group with dressing will be changed daily and will be assessed for healing week. There is no pain in simple dressing applied over cavity. Patient will receive broad spectrum antibiotics according to pus or tissue culture. During this period, laboratory investigation CBC, CRP will be sent to check the response. Sits bath will be advised to both groups. Post-operative pain, cavity healing will be assessed by faculty.

Enrollment: 70 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age greater than 18 years
• Age less than 70 years
• Perianal abscess

Exclusion criteria

• Suspected inflammatory bowel disease
• Fournier's gangrene
• Horseshoe/bilateral abscess

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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70 participants in 2 patient groups

Perianal abscess cavity packing

Active Comparator group

Treatment:

Procedure: No packing of perianal abscess cavity

Perianal abscess cavity no packing

Experimental group

Treatment:

Procedure: No packing of perianal abscess cavity