A Study of SGB-7342 in Subjects With Obesity or Overweight

Suzhou Sanegene Bio

Status and phase

Not yet enrolling

Phase 1

Conditions

Obesity & Overweight

Treatments

Drug: SGB-7342-Matching placebo

Drug: SGB-7342

Study type

Interventional

Funder types

Industry

Identifiers

NCT07324850

SGB-7342-001

Details and patient eligibility

About

The purpose of this study is to evaluate the safety and tolerability of subcutaneously administered SGB-7342 in adult subjects with obesity and overweight.

Enrollment

45 estimated patients

Sex

All

Ages

18 to 55 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Body Mass Index (BMI) within the range of 26.0 to 35.0 kg/m²
Have a stable body weight within 3 months
Participants must agree to use adequate contraception from signing the informed consent until 6 months after completion of the follow-up visit.
Willing to comply with the protocol required visit schedule and visit requirements and provide written informed consent.

Exclusion criteria

A history of or a current surgical or medical condition that, in the opinion of the Investigator, may put the subject at significant risk (according to Investigator's judgment) or interfere with the subject's participation in the clinical study.
Use of GLP-1R agonists for any indication within 6 months prior to administering the investigational drug.
Use of non-GLP1R medications for weight loss within 3 months prior to administering the investigational drug.
Alanine aminotransferase (ALT), total bilirubin (TBIL), aspartate aminotransferase (AST)> 1.5 × ULN, and deemed clinically significant by the Investigators