A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)

Mati Therapeutics

Status and phase: Completed; Phase 2

Conditions: Open-Angle Glaucoma; Ocular Hypertension

Treatments: Drug: Latanoprost

Study type: Interventional

Funder types: Industry

Identifiers

NCT00821002

PPL GLAU 05

Details and patient eligibility

About

The study objective is to compare IOP and safety outcomes based on plug placement (upper or lower puncta).

Enrollment: 32 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Over 18 years
• Diagnosed with bilateral Open-Angle Glaucoma or Ocular Hypertension

Exclusion criteria

• Uncontrolled medical conditions
• Subjects who wear contact lenses
• Subjects requiring chronic topical artificial tears, lubricants, and /or requiring any other chronic topical medications

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

32 participants in 1 patient group

Plug placement

Experimental group

Treatment:

Drug: Latanoprost