A Pilot C11-Choline PET-CT Imaging Study in Patients With Locally Advanced Esophageal Cancer

Wake Forest University (WFU)

Status and phase: Completed; Phase 1

Conditions: Esophageal Cancer

Treatments: Drug: C11-Choline

Study type: Interventional

Funder types: Other

Identifiers

NCT01051479

CCCWFU 60109 (Other Identifier)

IRB00012072

Details and patient eligibility

About

The purpose of this study is to evaluate the investigators ability to obtain reliable and meaningful 11C-Choline PET-CT images of esophageal cancer.

Enrollment: 22 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Newly diagnosed or recurrent patients with locally advanced esophageal cancer with either squamous or adenocarcinoma histology.
• Ability to tolerate PET imaging
• Prior malignancy is allowed, but the expectation of survival must be that beyond that expected for patients with locally advanced esophageal cancer.

Exclusion criteria

• Pregnant or lactating females are not eligible for this pilot study.
• Patients having received chemotherapy in the 3 months prior to registration for any reason
• Patients with metastatic disease requiring chemoradiation for palliation are not allowed.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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22 participants in 1 patient group

C11-Choline

Experimental group

Treatment:

Drug: C11-Choline