A Pilot Study of the Neural Correlates of Treatment Effect on Nicotine Craving
Status and phase
Completed
Phase 2
Conditions
Tobacco Use Disorder
Treatments
Drug: Topiramate
Study type
Interventional
Funder types
Other
Identifiers
Details and patient eligibility
About
The purpose of this study is to gather pilot data to determine feasibility of and guide the development of a larger clinical trial investigating the effects of topiramate as an adjunct to nicotine replacement therapy and behavioral counseling in smoking cessation treatment. It is hypothesized that topiramate will decrease nicotine craving and result in improved outcomes for smoking cessation.
Sex
Male
Ages
18 to 55 years old
Volunteers
No Healthy Volunteers
Inclusion criteria
- Male, between ages of 18-55
- Meets DSM-IV criteria for nicotine dependence
- Smoke at least 20 cigarettes per day
- Motivated to quit smoking
Exclusion criteria
- Serious or unstable medical conditions
- Current psychiatric disorder requiring medication or treatment
- Taking medication that create risk of interaction with study drug
- Current participation in another smoking cessation treatment
Trial contacts and locations
1
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Data sourced from clinicaltrials.gov
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