A Pilot Study on Efficacy and Safety of Ayurveda Combination in Patients With Mild-to-Moderate COVID-19

Aarogyam UK

Status

Completed

Conditions

Covid19

Treatments

Other: Shanshamani Vati Plus

Study type

Interventional

Funder types

Other

Identifiers

NCT04621903

AU/WU/ 06

Details and patient eligibility

About

The COVID-19 pandemic is considered as the most crucial global health concern of the century. Given the complex interaction of physical and social factors on fast spreading infection, there have been increasing calls for comprehensive efforts using a community-based participatory research (CBPR) approach.

CBPR partnership composed of representatives from community-based organisations, health and academia actively developed the present study. Specific aims were (1) to assess the efficacy and safety of Ayurvedic combination, Giloy (Tinospora Cordifolia) and Pippali (Piper longum) in the management of mild-to-moderate cases of COVID-19 and (2) to determine the effect in relieving COVID-19 symptoms and preventing the onset of severe infection.

Enrollment

26 patients

Sex

All

Ages

20 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

With SARS-CoV-2 infection confirmed through reverse transcription followed by polymerase chain reaction (RT- PCR),
With mild or moderate manifestations of COVID-19
Willing to participate, and consent by signing the informed consent and not involved in another clinical trial during the study period

Exclusion criteria

Patients suffering from severe COVID-19 Disease as judged by WHO criteria (REF)
Any of the known COVID-19 complications and emergency procedures which may require shift/admission in hospital for oxygen support or intensive care unit
Patients with ongoing immunosuppressive therapy for any reasons for example solid organ transplantation, autoimmune diseases or cancer.
Patients with known long term infection like HIV
Active cancer diagnosis, on palliative treatment or requiring current therapy with antimetabolic agents, immunotherapy or radiotherapy.
Pregnancy and lactation
Ayurveda practitioner decision that involvement in the study is not in the patient's best interest