A Pilot Study Simulating Multifocal Intraocular Lenses in Healthy Subjects

Medical University of Vienna

Status: Completed

Conditions: Visual Acuity; Contrast Sensitivity; Lenses, Intraocular

Treatments: Drug: Cyclopentolatehydrochloride

Study type: Observational

Funder types: Other

Identifiers

NCT01873781

OPTH-200912

Details and patient eligibility

About

Age related cataracts are responsible for about 51 percent of blindness worldwide and according to the WHO affect about 20 million people, according to the WH . As cataract surgery is firstline treatment in the western world, there is a constant attempt to improve artificial intraocular lenes (IOL).

As for this study, the investigators seek to compare four different IOL designs in in a psychophysiological setting, allowing to assess the impact of these IOLs on vision and psychological processing of visual information.

As these IOLs also have downsides, such as reduced light intensity or image alterations, the subjective preference and overall impression shall be investigated. The healthy subjects look through a stable spectacle frame mounted onto a table, which enables the investigator to insert the different IOLs. This would allow subjective testing of IOLs before surgery.

Enrollment: 30 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Men and women aged between 18 and 35 years

• Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
• Normal ophthalmic findings, between -1 and +1 diopters

Exclusion criteria

• > 0,5 diopters of cylinder
• Abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study
• Symptoms of a clinically relevant illness in the 3 weeks before the first study day

Trial design

30 participants in 1 patient group

30 healthy male and female subjects

Description:

30 healthy male and female subjects aged 18-35

Treatment:

Drug: Cyclopentolatehydrochloride