A Pilot Study to Test the Safety and Feasibility of a Brillouin Ocular Analyzer (Brillouin I)

Mass General Brigham

Status: Completed

Conditions: Measurement of the Elasticity of the Anterior Eye Segment

Treatments: Device: Brillouin Ocular Analyser

Study type: Interventional

Funder types: Other

Identifiers

NCT01775007

2008-P-002176/10

Details and patient eligibility

About

A Brillouin ocular analyzer uses a low-power near infrared laser light to probe the viscoelastic properties of the cornea and crystalline lens in the eye. The study hypothesis is that the instrument can measure the Brillouin light scattering spectra from the eye safely and effectively from human subjects.

Enrollment: 31 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy volunteers aged 20-60
• No refractional abnormalities
• Clear enough cornea and media to permit imaging

Exclusion criteria

• Occludable narrow angles (without a patent peripheral iridotomy)
• Other ocular or systemic pathology, which precludes safe eye dilation
• LASIK eye surgery
• Allergies to the dilation medication
• Only one healthy eye
• Pregnant women or expected pregnancy within the timeframe of the study
• Do not or cannot understand the instructions for the imaging
• Restricted mobility

Trial design

Primary purpose: Device Feasibility

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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31 participants in 1 patient group

Normal Healthy Subjects

Experimental group

Description:

Brillouin Ocular Analyser

Treatment:

Device: Brillouin Ocular Analyser