A Pilot Trial to Determine the Extent of Inter- and Intra-Treatment Organ Motion Using Active Breathing Control Device (ABC) in Patients With Pancreatic Cancer

University of Michigan Rogel Cancer Center

Status: Completed

Conditions: Pancreatic Cancer

Treatments: Radiation: Standard Radiation Therapy; Device: Active Breathing Control Device (ABC); Device: Computed Tomography Scan (CT)

Study type: Observational

Funder types: Other

Identifiers

NCT01986738

UMCC 2011.055

HUM00050677 (Other Identifier)

Details and patient eligibility

About

This is a study to assess the motion of pancreatic tumors during radiation therapy using Computed Tomography (CT) Scans and an Active Breathing Control (ABC) Device.

Enrollment: 9 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients ≥ 18 years of age
• A working diagnosis (with or without histologic confirmation) of pancreatic cancer
• A plan to treat with radiotherapy (or chemoradiotherapy)
• Patients must have fiducial marker(s) endoscopically placed within the pancreas for clinical treatment.

Exclusion criteria

• Previous abdominal radiotherapy.
• Patients with a history of major abdominal surgery.
• Patients who are pregnant.

Trial design

9 participants in 1 patient group

Radiation Treatment

Description:

Patients undergoing standard of care radiation treatment with Active Breathing Control (ABC)

Treatment:

Device: Computed Tomography Scan (CT)

Radiation: Standard Radiation Therapy

Device: Active Breathing Control Device (ABC)