A Population-based Study of Macular Choroidal Neovascularization in a Chinese Population

Shanghai University of Traditional Chinese Medicine

Status: Completed

Conditions: Geographic Atrophy; Wet Macular Degeneration; Retinal Drusen

Treatments: Other: Follow-up observation

Study type: Observational

Funder types: Other

Identifiers

NCT01666821

04-E-1

Details and patient eligibility

About

To investigate pathomorphological and functional variations of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) in a Chinese population using optical coherence tomography (OCT) to find which kinds of Fundus characteristics indicated exudative AMD.

Full description

This population-based study enrolled 59 patients (>45 years old; 70 eyes) with early and intermediate-stage AMD from Youyi Street, Baoshan District, Shanghai, China. Comprehensive standardized ophthalmic examinations included visual acuity, anterior segment analysis by slit lamp, dilated fundus evaluation by direct ophthalmoscopy, 90D handheld lens, fundus photography, fluorescein angiography (FFA), and fast optic disk scans using OCT. The macular CNV characteristic profiles in early and intermediate-stage AMD were determined by OCT. Data were obtained at first visit and 6 to 24 months follow-up, and FFA and OCT outcomes of early and intermediate-stage AMD patients were analyzed.

Enrollment: 59 patients

Sex: All

Ages: 45+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• adults citizens aged above 45 years

Exclusion criteria

• lost samples

Trial design

59 participants in 1 patient group

early and intermediate-stage AMD

Description:

Follow-up observation was implemented in whose fundus examination show lesions in the early and intermediate-stage AMD

Treatment:

Other: Follow-up observation