A Postoperative Sore Throat After Thyroidectomy

Yeungnam University College of Medicine

Status: Completed

Conditions: Post Operative Sore Throat

Treatments: Drug: remifentanil infusion group; Drug: dexmedetomidine infusion group

Study type: Interventional

Funder types: Other

Identifiers

NCT03805568

YUMC 2017-03-037

Details and patient eligibility

About

This study was performed to compare the effect on of a postoperative sore throat between dexmedetomidine and remifentanil in patients undergoing thyroidectomy.

Enrollment: 74 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who scheduled primary thyroidectomy were enrolled and their physical status was American Society of Anesthesiologists (ASA) class 1 or 2

Exclusion criteria

• Patients with respiratory tract disease, previous head, and neck surgery, preexisting steroid or non-steroidal anti-inflammatory drug use, and known or suspected difficult airway

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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74 participants in 2 patient groups

dexmedetomidine infusion group

Active Comparator group

Description:

dexmedetomidine infusion (loading dose of 1 ㎍/kg over 10 min and continuous infusion of 0.3-0.6 ㎍/kg/h) during the surgery

Treatment:

Drug: dexmedetomidine infusion group

remifentanil infusion group

Active Comparator group

Description:

remifentanil of 4 ng/ml during induction, followed by remifentanil infusion (1.5\~2.5 ng/ml) during the surgery

Treatment:

Drug: remifentanil infusion group