A Prediction Model of 28-day Mortality in Septic Shock

Zhejiang University

Status: Unknown

Conditions: Septic Shock

Study type: Observational

Funder types: Other

Identifiers

NCT04915625

2021-0603

Details and patient eligibility

About

This clinical study adopts the design of cohort research, selects the sepsis shock patients admitted to our hospital ICU as the research object, takes the 28-day mortality rate as the outcome index, collects the baseline data of the patient, the severity of the disease, vital signs, the main infection site, the laboratory-related index, the treatment method and other data, screens out the risk factors affecting the sepsis shock 28-day mortality rate and constructs the prediction model accordingly, analyzes the prediction model with the subject's working characteristic curve (ROC). The recognition ability of the model is calculated by the area under the ROC curve (AUC) and the ability of the model to predict 28-day mortality with SOFA and APACHE II.

Enrollment: 530 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age ≥ 18 years of age, gender-neutral;
2. Diagnosed with sepsis shock;
3. ICU survives longer than 48 h;
4. The preservation of clinical data is complete;

Exclusion criteria

• Diagnosed with sepsis shock within 6 hours of emergency treatment; Combined with people with autoimmune diseases; 3. Organ transplantation or immunosuppressive treatment; 4. Severe heart, liver and kidney insufficiency; 5. Late stage of malignant tumor; 6. Maternity; 7. Referral or referral to another hospital;

Trial design

530 participants in 2 patient groups

Death group

Description:

Retrospective observational studies

Survival group

Description:

Retrospective observational studies