A Prevalence Study of Obstructive Sleep Apnea in Subjects With Chest Pain, Positive Exercise Treadmill Test and Normal Coronary Angiogram

The University of Hong Kong (HKU)

Status: Terminated

Conditions: Endothelial Dysfunction; Cardiac Syndrome X; Obstructive Sleep Apnea

Treatments: Other: no intervention is involved in this study

Study type: Observational

Funder types: Other

Identifiers

NCT01217346

UW 09-127

Details and patient eligibility

About

Cardiac syndrome X consists of a triad of chest pain, abnormal exercise stress testing and normal coronary angiogram, and is hypothesized to be related to endothelial dysfunction. Endothelial dysfunction is also reported to be linked to obstructive sleep apnea. While chest pain can be one of potential presenting symptoms of obstructive sleep apnea, the investigators hypothesize that obstructive sleep apnea is common in subjects with cardiac syndrome X.

Enrollment: 20 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≧18 years, < 70 years
• Symptom of chest pain occurring at least once in the preceding year
• Positive exercise treadmill test
• Negative coronary angiogram
• Mentally fit to give informed consent

Exclusion criteria

• Mentally incapacitated persons
• Congestive heart failure
• Other potential causes of orthopnea (severe chronic obstructive pulmonary disease, persistent asthma)

Trial design

20 participants in 1 patient group

cardiac syndrome X

Description:

subjects fulfilling the clinical triad of cardiac syndrome X

Treatment:

Other: no intervention is involved in this study