A Prospective Cohort Study Of Myasthenia Gravis

Chongqing Medical University

Status: Unknown

Conditions: Myasthenia Gravis Crisis; Myasthenia Gravis

Treatments: Device: biomarkers

Study type: Observational

Funder types: Other

Identifiers

NCT04674605

2020-382

Details and patient eligibility

About

The average annual incidence of Myasthenia gravis is up to (8.0-20.0) / 100,000 people. Myasthenia gravis is an acquired autoimmune disease. All skeletal muscles of patients may be involved. When ocular muscles are involved, ptosis, diplopia and other symptoms may occur. When the laryngopharyngeal muscles are involved, the patient may develop dysarthria, dysphagia and other symptoms. However, when the respiratory muscles are involved, patients will have difficulty in breathing, and some patients may develope myasthenia crisis, and artificial assisted respiratory therapy is often needed.

This study is a prospective observational study, in which patients are continuously enrolled, basic information of patients is collected, and biological samples are collected. The purpose of this study is to improve the diagnosis and prognosis of myasthenia gravis patients.

Enrollment: 200 estimated patients

Sex: All

Ages: Under 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Meeting the diagnosis of myasthenia gravis

Exclusion criteria

• Malignant tumor or other serious chronic disease

Trial design

200 participants in 2 patient groups

ocular myasthenia gravis

Treatment:

Device: biomarkers

generalized myasthenia gravis

Treatment:

Device: biomarkers