A Prospective Comparison of Cardiac Troponin T and Troponin I in the Diagnosis of Myocardial Infarction

Herlev Hospital

Status: Enrolling

Conditions: Myocardial Infarction

Treatments: Diagnostic Test: Troponin T and I

Study type: Observational

Funder types: Other

Identifiers

NCT04087538

19000557

Details and patient eligibility

About

The rising number of patients with chest pain without myocardial infarction has made accurate diagnosis important. Unnecessary invasive coronary angiographies are increasingly prevalent. These are both costly and lead to rare but serious adverse events. Recent studies suggest cardiac Troponin I is more cardiac specific than cardiac Troponin T. In this study we will investigate whether using cardiac Troponin I lead to fewer unnecessary procedures in clinical practice (i.e. invasive coronary angiography and non-invasive tests)

Enrollment: 300 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admitted to either Herlev-Gentofte or Amager-Hvidovre Hospital
• Clinically suspected of NSTEMI
• Referred to invasive coronary angiography (ICA)
• Recieved at least one measurement of either troponin

Exclusion criteria

Trial design

300 participants in 2 patient groups

Patients treated using troponin T

Treatment:

Diagnostic Test: Troponin T and I

Patients treated using troponin I

Treatment:

Diagnostic Test: Troponin T and I