A Prospective Comparison of Ultrasound-Guided Percutaneous Platelet-Rich Plasma Injection

University of Michigan

Status and phase: Completed; Phase 2

Conditions: Tendinitis; Tendinosis

Treatments: Procedure: Tenotomy (no injection); Drug: Ultrasound guided platelet rich plasma injection

Study type: Interventional

Funder types: Other

Identifiers

NCT01600326

HUM00039445

Details and patient eligibility

About

The purpose of this study is to determine the effectiveness of various treatment soft tendinosis also known as tendinitis.

Full description

Currently there are three treatments that are considered standard of care; rest, tenotomy and tenotomy with injections of platelet-rich plasma (PRP). Tenotomy is performed by passing a needle through the abnormal tendon repeatedly until the needle has passed through all areas of the abnormal tendon with softening of the tendon. Tenotomy with PRP injections is performed in the same manner but includes an injection of platelet-rich plasma (PRP) into the tendon. This study will evaluate the effectiveness of tenotomy versus PRP treatment.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult subjects with a diagnosis of tendinosis of the hip.
• Adult subjects who have been referred to Dr. Jacobson for the treatment of tendinosis by tenotomy.

Exclusion criteria

• pregnancy
• risk of bleeding due to anticoagulant medication
• presence of malignancy
• steroid injection less than 3 months before enrollment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

Tenotomy Group

Active Comparator group

Description:

Subject enrolled in this arm will receive treatment for tendinitis and pain evaluation of pain pre and post treatment.

Treatment:

Procedure: Tenotomy (no injection)

Plasma Injection Group

Active Comparator group

Description:

Treatment is Ultrasound guided platelet rich plasma injection.

Treatment:

Drug: Ultrasound guided platelet rich plasma injection