A Prospective Controlled Study on Treatment of Giant Cavernous Hemangiomas of the Liver

Army Medical University

Status

Completed

Conditions

Laparoscopic Hepatectomy

Giant Cavernous Hemangiomas

Radio-frequency Ablation

Liver

Treatments

Procedure: RFA

Procedure: hepatectomy

Study type

Interventional

Funder types

Other

Identifiers

NCT01471080

swhb004

Details and patient eligibility

About

In the past, the investigators often treated giant cavernous hemangiomas of the liver by hepatectomy.Recently RFA and laparoscopic hepatectomy are also available and could be applied to cure this disease.But we can't get a clear answer about their effectiveness and safety. Hence the investigators conduct this study to explore the effectiveness and efficiency of the these two methods and compare their short to mid-term outcomes.

Enrollment

140 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

giant cavernous hemangiomas with a diameter larger than or equal to 5 cm diagnosed by more than one imaging modalities
age between 18 years to 65 years
without gender restriction
PLT account more than 50 e9
without abnormal of liver function test
with substantial evidence of growing size than before
symptom associated cavernous hemangiomas
with a strong desire of the patients for the treatment

Exclusion criteria

pregnant women
abnormal of liver function or coagulation dysfunction and/or concurrent with sever cardiac or pulmonary disorders
patient with a poor condition that can't bear the approach of either RFA or laparoscopic hepatectomy
tumor size more than 20cm