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Currently, there is no official recommendations for the respiratory surveillance of patients with PID.However, it is recommended to perform a chest CT scan each 5 years or before any significant therapeutic change.
The methods of surveillance need to meet two contradictory imperatives:
To make thoses requirements effective, the solution is to combine radiological monitoring and absence of irradiation. Therefore, it makes sense to study whether chest scans can be replaced by MRI, non-irradiating imaging. But the question that needs to be answered is whether the information provided by the chest MRI is not inferior to that provided by the scanner.
The objective of this study is to assess the ability of MRI performed with ultrashort echo time to analyze the extent and severity of bronchial and pulmonary parenchymal lesions during the follow-up of patients with primary immunodeficiency, comparing them to those of the chest CT scan.
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Pregnant woman
Contraindications to MRI:
To be deprived of liberty or under guardianship.
Primary purpose
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Interventional model
Masking
50 participants in 1 patient group
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Central trial contact
Elisabeth Hulier-Ammar,PHD; Virginie Guitard
Data sourced from clinicaltrials.gov
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