A Prospective Multicenter Observational Real-world Study of Retained Products of Conception

Central South University

Status: Enrolling

Conditions: RPOC; Retained Products of Conception

Treatments: Drug: Expectant care; Procedure: Uterine curettage

Study type: Observational

Funder types: Other

Identifiers

NCT07421895

fkky2022001

Details and patient eligibility

About

The purpose of this study is to explore the optimal treatment strategy for retained products of pregnancy. Compared with surgical treatment, prospectively observe whether drug-assisted expectant management until the right time for surgery reduce the occurrence of intrauterine adhesions, and thus protect fertility.

Enrollment: 600 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Clinical diagnosis of retained products of conception, and ultrasound indicated that the maximum diameter of the lesion ≥0.5cm.

Exclusion Criteria:1) There is active bleeding requiring immediate surgical intervention;2) combined with obvious infection;3) Combined with severe organ dysfunction, including coagulation dysfunction.

Trial design

600 participants in 2 patient groups

Control group

Description:

After the patient is confirmed to be included in the study, he/she will be hospitalized directly and will undergo hysteroscopic removal of pregnancy products.

Treatment:

Procedure: Uterine curettage

Experimental group

Description:

Wait until a certain time, then surgical treatment if necessary

Treatment:

Drug: Expectant care