A Prospective, Randomized Clinical Study on the Effects of Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) Paste on Plaque, Gingivitis and White Spot Lesions in Orthodontic Patients - Part 1

Ghent University Hospital (UZ)

Status: Completed

Conditions: Early Caries Lesions

Treatments: Device: CPP-ACP (GC MI Paste Plus); Device: CPP-ACP (GC Tooth Mousse)

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00670670

2008/187 - Part 1

Details and patient eligibility

About

Influence of CPP-ACP paste on the evolution and appearance of white spot lesions in orthodontic patients after removal of the fixed appliances.

Enrollment: 325 patients

Sex: All

Ages: 10 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• one or more white spot lesion at the time of removal of fixed appliances

Exclusion criteria

• white spots already present before start orthodontic treatment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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325 participants in 3 patient groups

1

Experimental group

Description:

CPP-ACP (GC Tooth Mousse)

Treatment:

Device: CPP-ACP (GC Tooth Mousse)

2

Experimental group

Description:

CPP-ACP (GC MI Paste Plus)

Treatment:

Device: CPP-ACP (GC MI Paste Plus)

3

No Intervention group

Description:

Control group