A Prospective Study of Early Mechanical Stabilization and Bleeding in Disruption of the Pelvic Ring (EMS-BIND)

Major Extremity Trauma Research Consortium

Status: Invitation-only

Conditions: Pelvic Fracture

Treatments: Procedure: Application of circumferential pelvic compression (CPC) device

Study type: Observational

Funder types: Other

Identifiers

NCT03977168

W81XWH-16-2-0060-EMS-BIND

Details and patient eligibility

About

The objective of this study is to evaluate the effect of earlier placement of Circumferential Pelvic Compression (CPC) on resuscitative measures required for life-threatening pelvic ring injuries and to guide the development of future efficacy trials of three advanced resuscitation techniques (surgical pelvic packing, angioembolization, REBOA).

Enrollment: 600 estimated patients

Sex: All

Ages: 18 to 64 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient age between 18 and 64 years, inclusive;
• Severe blunt or blast traumatic injury;
• Young-Burgess APC-2 and 3, LC-3, vertical shear, and combined mechanism of injury (CMI) (Tile B and C patterns; OTA codes 61-B and 61-C);
• Circumferential pelvic compression (CPC) device used at any time within 24 hours of injury.
• Patient must speak either English or Spanish

Exclusion criteria

• Arrival to hospital of definitive care more than 6 hours after injury;
• Ballistic pelvic injury, other than from a blast mechanism;
• Time of CPC placement not recorded;
• Time of injury and time of EMS dispatch unknown;
• Use of medical anti-shock trousers (MAST);
• Confirmed dead on arrival to hospital