A Prospective Study to Evaluate MRI Guided Biopsy Compared With Transrectal Ultrasound Guided Biopsy of the Prostate in Men With Increased PSA Values

Heinrich-Heine University, Duesseldorf

Status: Completed

Conditions: Prostate Cancer

Treatments: Device: MRI guided prostate biopsy and TRUS guided biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT01553838

002

Details and patient eligibility

About

The purpose of this study is to determine whether MRI guided prostate biopsy achieves higher prostate cancer detection rates compared with transrectal ultrasound guided prostate biopsy in patients with increased PSA values > 4.0 ng/ml.

Enrollment: 185 patients

Sex: Male

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• PSA > 4.0 ng/ml
• written informed consent
• age >18

Exclusion criteria

• patients with prostate cancer
• patients with prior prostate biopsy
• patients with contraindications against MRI or biopsy

Trial design

185 participants in 1 patient group

Sequentially MRI guided and TRUS guided biopsy

Experimental group

Description:

Targeted MRI guided biopsy according to findings in a multiparametric MRI followed by transrectal guided biopsy

Treatment:

Device: MRI guided prostate biopsy and TRUS guided biopsy