A Protocol for the Use of Chlorhexidine Gluconate Saturation for the Reduction of Dental Biofilm Formation on Polymethylmethacrylate Restoration

Hadassah Medical Center

Status and phase: Completed; Phase 1

Conditions: Dental Plaque

Treatments: Procedure: saturation of polymethylmethacrylate with chlorhexidine gluconate to reduce in vivo plaque formation

Study type: Interventional

Funder types: Other

Identifiers

NCT00259181

191058HMO-CTIL

Details and patient eligibility

About

Chlorhexidine gluconate (CHX), as an anti plaque agent, is commonly used with a variety of products. In this study we, the investigators at Hadassah Medical Organization, intend to examine the efficacy of a single dip in CHX of provisional restoration prior to oral cementation. If the protocol is effective, we intend to calibrate it and recommend clinical use of the protocol. The examination of biofilm formation will be both with electron microscope and confocal scanning laser microscope.

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Any volunteer without systemic condition

Exclusion criteria

• Intake of antibiotic drug three months prior to experiment

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: Single Blind