A Randomised Study Comparing Tissue Conservation in Conventional Versus Mohs' Surgery of Basal Cell Carcinoma

NHS Tayside

Status: Completed

Conditions: Carcinoma, Basal Cell

Treatments: Procedure: standard surgery; Procedure: Mohs micrographic surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT00571363

2003DS10

R&D Project ID: 2003DS10

Details and patient eligibility

About

We have compared to types of surgery to assess which one leaves the smaller surgical defect.

Full description

Patients with a clinical diagnosis of a nodular basal cell carcinoma of less than 1 centimetre and 1 centimetre away from eyes, nose and ears were either randomized to undergo Mohs Micrographic Surgery or standard surgical excision. After the tumour had been removed the defect was measured.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects with a clinical diagnosis of a nodular basal cell carcinoma of less than 1 cm, 1 cm away from eye, nose or ears

Exclusion criteria

• Subjects of less than 18 years of age
• Subjects unable to comply with instructions,
• Immunosuppressed subjects

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

standard surgery

Active Comparator group

Description:

basal cell carcinomas were excised with 4 mm margins

Treatment:

Procedure: standard surgery

Mohs

Active Comparator group

Description:

Basal cell carcinoma were removed via Mohs Micrographic surgery

Treatment:

Procedure: Mohs micrographic surgery