A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain

The University of Texas System (UT)

Status and phase

Terminated

Phase 4

Conditions

Pain, Postoperative

Treatments

Drug: Bupivacaine hydrochloride

Drug: Intrathecal morphine sulfate (ITM)

Drug: ropivacaine hydrochloride

Study type

Interventional

Funder types

Other

Identifiers

NCT04368364

HSC-MS-20-0143

Details and patient eligibility

About

the purpose of this study is to compare opioid consumption in morphine equivalents between the groups that received postoperative analgesia with intrathecal morphine versus US guided QL blocks versus US guided QL catheters

Enrollment

3 patients

Sex

Female

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Elective C section via Pfannenstiel incision
Living singleton pregnancy
Gestation week at least 37 weeks
American Society of Anesthesiologists (ASA) status 1, 2 and 3
Primary and secondary C sections

Exclusion criteria

Chronic pain
Opioid tolerant patients
Allergy to drugs used in the study.
Cognitive dysfunction
BMI > 40
Coagulation disorder
Local infection
Inability to tolerate oral medication
Previous intra-abdominal surgery
Patients who will receive a combined spinal epidural for their C section
Local anesthetics injected at any other fascial plane except the QLB plane (for e.g.- local wound infiltration by surgeon)
Patients who received sedation or general anesthesia during their C section (midazolam, ketamine, fentanyl, propofol, hydromorphone)