A Randomized Controlled Trial Evaluating the Role of Negative Pressure Wound Therapy (NPWT) for Incisional Surgical Site Infections in Patients Undergoing Hepatopancreatobiliary Surgery

Murk Niaz

Status: Completed

Conditions: Surgical Site Infection; Hepatobiliary Disease; Hepatobiliary Disorders

Treatments: Other: Negative Pressure Wound Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT05481398

NPWT HPB

Details and patient eligibility

About

To compare the rates of incisional surgical site infections (iSSIs) within 7 days of hepatopancreatobiliary (HPB) surgery using negative pressure wound therapy (NWPT) versus using standard sterile gauze dressing.

Enrollment: 46 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All patients undergoing elective open HPB surgery (benign or malignant disease) of age > 18 years consenting to the study protocol.

Exclusion criteria

The patient in which primary wound closure is not achieved. The patient planned for a second look surgery. The patient with the history of long-term antibiotic use (more than a month). Past history of open abdominal surgery (less than 1 month).

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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46 participants in 2 patient groups

Intervention group A

Experimental group

Description:

After the skin closed, negative pressure wound therapy will be applied.

Treatment:

Other: Negative Pressure Wound Therapy

Control group B

No Intervention group

Description:

After the skin is closed, the wound is covered using sterile standard guaze dressing.