A Randomized Cross-over Trial of the Postprandial Effects of Three Different Diets in Patients With Type 2 Diabetes

Vårdcentralen Lyckorna

Status: Completed

Conditions: Type 2 Diabetes Mellitus

Treatments: Dietary Supplement: Low-fat Diet; Dietary Supplement: Mediterranean Diet; Dietary Supplement: Low-carbohydrate Diet

Study type: Interventional

Funder types: Other

Identifiers

NCT01522157

Dnr 2011/418-31

Details and patient eligibility

About

The trial will study the acute metabolic effects of three different types of diet: low-fat diet, low-carbohydrate diet and Mediterranean diet. About 20 patients with diabetes mellitus type 2 will be recruited and each of them will be given each type of diet on three different days. Menus with the same energy content but with different content of fat, carbohydrate and protein are designed. Breakfast and lunch are served for the patients each day of testing. Laboratory samplings are performed six times during the day. The order of the dietary intervention is randomized for each patient.

The investigators suppose to find different reaction in plasma glucose and lipids depending on the type of diet.

Enrollment: 19 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetes mellitus type 2

Exclusion criteria

• Treatment with insulin or sulfonylurea

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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19 participants in 1 patient group

All test patients

Active Comparator group

Description:

All test patients are given low-fat, low-carbohydrate and mediterranean diet, in randomised order on different days.

Treatment:

Dietary Supplement: Low-carbohydrate Diet

Dietary Supplement: Low-fat Diet

Dietary Supplement: Mediterranean Diet