A Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China (CLM-tree datab)

Guangzhou Medical University

Status: Enrolling

Conditions: Meningeal Metastasis; Non-Small Cell Lung Cancer

Treatments: Other: Not applicable- observational study

Study type: Observational

Funder types: Other

Identifiers

NCT06718972

ES-2024-K125-02

Details and patient eligibility

About

This is a retrospective and prospective study planned to include NSCLC patients with Leptomeningeal metastasis (LM) and treated with antitumor therapy after 2018, from multiple centers such as the First Affiliated Hospital of Guangzhou Medical University, Guangdong Sanjiu Brain Hospital, etc., aiming to establish a database related to the treatment strategies of LM patients, and to evaluate the efficacy (eg. Overall Survival/Time to Failure) and safety of different treatment strategies of LM patients, etc., as well as the significance of concomitant testing in LM patients.

Full description

retrospective and prospective study

Enrollment: 1,000 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• non-small cell lung cancer patients with Leptomeningeal metastases diagnosed after January 2018;
• Patients who underwent antitumor therapy after diagnosis of LM.

Exclusion criteria

• Patients with small cell lung cancer components;
• complicated with tumors other than non-small cell lung cancer.