a. Reducing Radioiodine Treatment in Papillary Thyroid Cancer. RAILESS

Helsinki University Central Hospital (HUCH)

Status: Active, not recruiting

Conditions: to Omit Radioiodine Treatment Safely in Patients With Low -Risk Papillary Thyroid Cancer With Seize of 11-20mm

Treatments: Other: With radioiodine treatment; Procedure: With postoperative radioiodine treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT06271044

RAILESS

Details and patient eligibility

About

To study if its is safe to reduce the amount of postoperative treatments in those patients, who have been operated on because of a low-risk intrathyroidal papillary thyroid cancer with diameter of 11-20mm, and in whom postoperative thyroglobulin levels are of low level.

Full description

The purpose of the study : to enroll about 50 patients operated on because of a low-risk intrathyroidal papillary thyroid cancer with diameter of 11-20mm, and in whom postoperative thyroglobulin levels are of low level.

Methods: either to follow-up patients according to the study protocol without radioiodine treatment or to give a radioiodine treatment with a dose of 1.1 GBq according to the normal Finnish treatment protocol for papillary thyroid cancer to those patients who themselves preferred to have a normal postoperative treatment.

Enrollment: 61 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• low risk papillary intrathyroidal thyroid cancer with diameter of 11-20mm
• no lymphnode metastases

Exclusion criteria

• high risk papillary cancer
• mutlifocal papillary cancer

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

61 participants in 2 patient groups

RAILESS

No Intervention group

Description:

Railess group including patients to bw followed up wihtout postoperative radioiodine treatment

rairinn

Active Comparator group

Description:

THose patients receiving radioiodine treatment according to the normal treatment practice at that time

Treatment:

Procedure: With postoperative radioiodine treatment

Other: With radioiodine treatment