A Registered Cohort Study on α-Synucleinopathy

Fujian Medical University (FJMU)

Status: Enrolling

Conditions: α-synucleinopathy

Treatments: Other: Data collection

Study type: Observational

Funder types: Other

Identifiers

NCT05527067

Cohort-PDS

Details and patient eligibility

About

α-Synucleinopathy is a cluster of neurodegenerative disease with motor and non-motor symptom. The data to be collected is intended to help healthcare providers make important medical decisions concerning α-synucleinopathy, through an enhanced understanding of the natural history, progression and multi-omics datasets of α-synucleinopathy.

Full description

α-Synucleinopathy is a cluster of neurodegenerative disease with motor and non-motor symptom, including Parkinson's disease (PD), multiple system atrophy (MSA) and dementia with lewy bodies (DLB). The data to be collected is intended to help healthcare providers make important medical decisions concerning α-synucleinopathy, through an enhanced understanding of the natural history, progression and multi-omics datasets of α-synucleinopathy. Datas will be accumulated retrospectively at research entry and prospectively during follow up.

Enrollment: 500 estimated patients

Sex: All

Ages: 30 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants with a clinical diagnosis of primary α-synucleinopathy
• Unrelated healthy controls

Exclusion criteria

• Patients with secondary α-synucleinopathy that cannot be excluded.
• Patients with other neurological disorders.
• Pregnant or lactating women.

Trial design

500 participants in 2 patient groups

α-synucleinopathy

Description:

Participants with clinical diagnosis of α-synucleinopathy.

Treatment:

Other: Data collection

Other: Data collection

Healthy controls

Description:

Healthy controls

Treatment:

Other: Data collection

Other: Data collection