A Registered Cohort Study on Wilson's Disease

Wan-Jin Chen

Status: Enrolling

Conditions: Wilson's Disease

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04012658

MRCTA,ECFAH OF FMU[2019]197

Details and patient eligibility

About

The aim of this study is to determine the clinical spectrum and natural progression of Wilson's Disease in a prospective multicenter natural history study, to assess the clinical, genetic, epigenetic features and biomarkers of patients with Wilson's Disease to optimize clinical management.

Enrollment: 2,000 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with the genetic diagnosis of Wilson's Disease
• Asymptomatic Wilson's Disease carriers
• Relatives of Wilson's Disease patients or carriers
• Unrelated healthy controls
• Participants or Parent(s)/legal guardian(s) willing and able to complete the informed consent process

Exclusion criteria

* Participants are unable to comply with study procedures and visit schedule

Trial design

2,000 participants in 4 patient groups

Patients with the genetic diagnosis of Wilson's Disease

Treatment:

Other: No intervention

Asymptomatic Wilson's Disease carriers

Treatment:

Other: No intervention

Relatives of Wilson's Disease patients or carriers

Treatment:

Other: No intervention

Unrelated healthy controls

Treatment:

Other: No intervention