A Registry for Nontuberculous Mycobacterial Pulmonary Disease

Yonsei University

Status: Invitation-only

Conditions: Nontuberculous Mycobacterial Pulmonary Disease

Study type: Observational

Funder types: Other

Identifiers

NCT04078412

4-2017-0958

Details and patient eligibility

About

Background:

NTM(Nontuberculous mycobacteria) pulmonary disease is increasing worldwidely, however the diagnosis and treatment of NTM pulmonary disease still has multiple obstacles. The initiation of treatment is not necessary for all patients with NTM pulmonary disease. In addition, the drugs for treatment of NTM pulmonary disease is not enough.

objective. The aim of this prospective registry for Nontuberculous mycobacterial pulmonary disease is to register the NTM pulmonary patients and analysis of the treatment outcome based on the species and to collect the blood and urine samples from the patients for exploring the biomarker for diagnosis and monitoring the NTM pulmonary disease and collect the nontuberculous mycobacterium.

Methods:

1. informed consents
2. register in cohort and collect the clinical information and serum, plasma, urine and mycobacteria
3. follow up 6 months to 1year based on the clinical situation

Analysis:

1. treatment outcome based on NTM-NET consensus statement
2. exploration of biomarker for progression and monitoring of treatment response

Enrollment: 114 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. age 20 or more than 20 years
2. diagnosed by ATS criteria for NTM pulmonary disease

Exclusion criteria

1. not specific

Trial design

114 participants in 1 patient group

NTM pulmonary disease

Description:

Cohort Description: adults NTM pulmonary disease patients diagnose by criteria of American thoracic society guideline