A Registry of AL Amyloidosis (ReAL)

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Enrolling

Conditions: AL Amyloidosis

Study type: Observational

Funder types: Other

Identifiers

NCT04839003

AC-018-IT

Details and patient eligibility

About

The purpose of this protocol is to generate a large registry of patients with AL amyloidosis.

Full description

Thanks to this registry, it will be possible to collect data at diagnosis and during follow up, in order to be able to describe the natural history of AL amyloidosis in a real-world setting and to define and validate prognostic models, response and relapse criteria applicable at any point of the disease.

Enrollment: 5,000 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. diagnosis of systemic AL amyloidosis;
2. treatment-naïve (pre-treatment data collected at participating center available for retrospective part);
3. age ≥18 years;
4. ability to understand and willingness to sign an informed consent (patients who already sign informed consent for clinical data to be used in retrospective analyses will be accepted);
5. planned (or ongoing) follow-up at participating center.

Exclusion criteria

1. non-AL amyloidosis;
2. previous treatment for AL amyloidosis.