A Registry Study on Rimegepant for the Treatment of Migraine Participants in Guangdong-Hong Kong-Macao Greater Bay Area

Sun Yat-sen University

Status: Enrolling

Conditions: Migraine

Treatments: Drug: Rimegepant

Study type: Observational

Funder types: Other

Identifiers

NCT06221267

SYSKY-2023-1172-01

Details and patient eligibility

About

This study is a single-arm, prospective, multicenter, observational registry study. It plans to enroll 120 migraine patients who meet the inclusion criteria and are treated with rimegepant in selected hospital outpatient clinics in the Greater Bay Area. The main purpose of this study is to observe the effectiveness of rimegepant in treating migraines in a real-world clinical setting, including the impact of rimegepant on the quality of life, functioning, productivity status of migraine patients, and patients' satisfaction with the use of rimegepant in treating migraines.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants with headaches that meet the diagnostic criteria for migraines according to the International Classification of Headache Disorders, 3rd edition (ICHD-3), with or without aura.
• Patients prescribed rimegepant by the attending physician for the treatment of migraines.
• Signed informed consent form.
• Age greater than 18 years.
• Not concurrently participating in other interventional clinical studies.

Exclusion criteria

• Patients diagnosed with secondary headaches.
• Patients with severe visual, auditory, language, intellectual, memory, consciousness impairments or other conditions that prevent them from completing the questionnaire and follow-up.
• Pregnant or lactating female patients.
• Patients deemed by the investigator as unsuitable for participation in the study or unable to complete the 4-week follow-up.
• Patients with a known history of hypersensitivity reactions to rimegepant or its components.
• Evidence in the medical history suggesting the presence of uncontrolled or unstable cardiovascular diseases (such as ischemic heart disease, coronary artery vasospasm, or cerebrovascular ischemia), or a history of myocardial infarction, acute coronary syndrome, percutaneous coronary intervention, cardiac surgery, stroke, or transient ischemic attack within the past 6 months before the screening visit.