A Research Study Looking at Specific Tissue of the Umbilical Cord
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About
The purpose of this study is to isolate Umbilical cord Wharton's jelly matrix to be used as a scaffold for tissue regenerative applications, including avascular necrosis.
Full description
Our working hypothesis is that umbilical cord blood Wharton's Jelly matrix has all the biochemical and biomechanical characteristics needed in an ideal scaffold for tissue engineering. Accordingly, we expect matrix to support the growth and differentiation of transplanted mesenchymal stem cells. The first step in this effort is to isolate Wharton's Jelly matrix by decellularization. The second step will be to test the ability of this matrix to support the growth and differentiation of transplanted mesenchymal stem cells. The third step will be to pursue preliminary animal testing to study the ability of this matrix to support bone tissue regeneration in vivo.
Enrollment
Sex
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Volunteers
Inclusion criteria
- Pregnant Women
- 18 years of age or older
- willing to donate umbilical cord units
Exclusion criteria
- less than 18 years of age
- Has Hepatitis or HIV
- Considered High Risk
- Scheduled for C-Section due to complications during current pregnancy
- Delivered prior to Full Term
Trial design
64 participants in 1 patient group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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