A Retrospective Analysis of Robot-Assisted Versus Endoscopic Breast-Conserving Surgery for Breast Cancer

Sun Yat-sen University

Status

Enrolling

Conditions

Breast Cancer

Breast Surgery

Treatments

Procedure: Robotic breast-conserving surgery

Procedure: Endoscopic breast-conserving surgery

Study type

Interventional

Funder types

Other

Identifiers

NCT07321145

2025ZSLYEC-374

Details and patient eligibility

About

Robotic surgical systems provide notable advantages including enhanced dexterity, a magnified three-dimensional high-definition view, and high-resolution imaging, thereby improving operative stability and precision. These features make robotic systems particularly suitable for procedures performed within confined operative spaces. As the breast is a solid organ without a natural cavity, robotic systems demonstrate strong adaptability for breast surgery. Robot-assisted breast-conserving surgery (RABCS) is one of the currently utilized robotic techniques in clinical breast cancer surgery. However, as robotic breast surgery remains in its early stage of development, evidence regarding the clinical outcomes of RABCS remains limited in the literature. Therefore, this study compares the surgical outcomes of endoscopic breast-conserving surgery and robot-assisted breast-conserving surgery in breast cancer patients, aiming to assess and elucidate the clinical value of RABCS.

Enrollment

200 estimated patients

Sex

Female

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Female patients aged 18 to 80 years
Pathologically confirmed breast cancer prior to surgery
Sufficient glandular volume with a tumor-to-breast volume ratio ≤20%
A unifocal lesion confined to the glandular tissue
Clear desire for breast conservation and willingness to undergo R-BCS or E-BCS
No evidence of distant metastasis, no involvement of the skin or chest wall
Eligibility for standard postoperative radiotherapy

Exclusion criteria

The presence of diffuse suspicious lesions or microcalcifications for which wide local resection was unlikely to achieve adequate negative margins or satisfactory aesthetic outcomes
Bilateral breast cancer or inflammatory breast cancer
After neoadjuvant therapy, requirement for additional concurrent surgical procedures
Inability to tolerate general anesthesia or undergo surgery
Contraindications to radiotherapy or a history of prior chest wall irradiation, pregnancy- or lactation-associated breast cancer
Refuse to undergo R-BCS or E-BCS