A Retrospective Cohort Study to Develop Markers for TB Severity and Treatment Progress

Jae-Joon Yim

Status: Not yet enrolling

Conditions: Tuberculosis, Pulmonary; Pulmonary Tuberculoses

Treatments: Other: Medical records review

Study type: Observational

Funder types: Other

Identifiers

NCT05477966

H-2206-179-1336

Details and patient eligibility

About

The objective of this study is to compare how accurately the Xpert MTB/RIF assay Ct value at diagnosis and the AI-based tuberculosis activity score predict the treatment outcome of rifampin-susceptible pulmonary tuberculosis patients. As a retrospective observational study, data from patients diagnosed with rifampin susceptible pulmonary tuberculosis through the Xpert MTB/RIF assay performed on sputum in 2019 at the participating institutions will be analyzed (up to 900 people).

Enrollment: 900 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with rifampin-susceptible pulmonary tuberculosis by Xpert MTB/RIF assay with sputum samples between January 1, 2019 and December 31, 2019

Exclusion criteria

• None