A Retrospective EGFR Mutation Status Study in Chinese NSCLC Patients Using Paired Plasma and Tissue Samples

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Unknown

Conditions: Carcinoma, Non-Small-Cell Lung

Study type: Observational

Funder types: Other

Identifiers

NCT01382992

LCC001

Details and patient eligibility

About

EGFR mutations plays an essential role in EGFR-TKIs treatment. However, for some patients, tissue samples are not available. The purpose of this study is to determine whether blood sample is feasible for EGFR mutation detection.For late stage NSCLC, we hypothesis plasma sample is an alternative for detecting EGFR mutations.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Non-small cell lung cancer
• Available plasma and pathologically confirmed tissue slices(pre-chemo and pre-radio therapy)
• Informed Consent

Exclusion criteria

• N/A

Trial design

150 participants in 2 patient groups

Early Stage

Late Stage