A Short-term Mixed Exercise for Sarcopenic Hospitalized Aged 80+ Years

Yuxiang Liang

Status: Completed

Conditions: Sarcopenia

Treatments: Behavioral: balance training; Behavioral: aerobic exercise; Behavioral: usual care; Behavioral: resistance training

Study type: Interventional

Funder types: Other

Identifiers

NCT04355299

2019#611#

Details and patient eligibility

About

Most previous clinical trials that addressed exercise for sarcopenic elderly subjects focused on community-dwelling older adults who were relatively healthy. There is a notable paucity of high-quality research investigating the effects and feasibility of exercise for hospitalized or institutionalized older people, who are generally frailer and more severe in functional impairment than those living in the community. Moreover, most reported exercise programs were of long-term duration, which typically lasted 3 to 6 months with two sessions per week. It remains unclear whether short-term exercise would be effective for treating sarcopenia. Therefore, the investigators aimed to assess the effectiveness of short-term exercise for treating sarcopenia in hospitalized older patients aged 80 years and over.

Enrollment: 121 patients

Sex: All

Ages: 80 to 102 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. aged ≥80 years;
2. being able to ambulate (assistance was acceptable);
3. being able to communicate and collaborate with the physiotherapist;
4. with sarcopenia defined by the AWGS criteria ;

Exclusion criteria

1. terminal illness;
2. uncontrolled heart failure;
3. myocardial infarction within the past three months;
4. uncontrolled respiratory failure;
5. bone fractures within the past three months;
6. acute pulmonary embolism;
7. major surgery within the past three months;
8. uncontrolled arrhythmia;
9. refusal to participate in this study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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121 participants in 2 patient groups

Intervention group

Experimental group

Description:

a mixed exercise program including aerobic, balance, and resistance exercises that were personally tailored.

Treatment:

Behavioral: balance training

Behavioral: aerobic exercise

Behavioral: resistance training

control group

Other group

Description:

usual care

Treatment:

Behavioral: usual care