Investigating the Impact of Nudging Cardiologists to Prescribe Guideline-directed Medical Therapy in Heart Failure Patients (ADMINISTER II)

Medisch Spectrum Twente

Status: Enrolling

Conditions: Heart Failure

Treatments: Combination Product: Nudging

Study type: Interventional

Funder types: Other

Identifiers

NCT06844006

ADMINISTER II

Details and patient eligibility

About

This study investigates the impact of a nudge-based intervention on improving guideline directed medical therapy (GDMT) prescription among cardiologists. Using a stepped wedge randomized controlled trial design, we assess whether digital decision support-leveraging home monitoring and clinical data-enhances adherence to guideline-recommended medication titration. The primary outcomes include HF related hospitalization rates and all cause mortality.

Enrollment: 1,320 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All heart failure diagnoses
• >18 years

Exclusion criteria

• Not understanding the Dutch Language.
• Allergies that make uptitration impossible.
• Admission to hospice or palliative care.
• Severe psychological disorders.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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1,320 participants in 1 patient group

Intervention

Other group

Description:

All cardiologists will be nudged during the trial. with the use of a stepped wedge design there will be a structured embedding in the current standard of care.

Treatment:

Combination Product: Nudging