A Study Comparing Etoricoxib and Diclofenac Sodium in Post Hallux Valgus Surgery Pain

Karolinska Institute

Status and phase: Withdrawn; Phase 4

Conditions: Postoperative Pain; Hallux Valgus

Treatments: Drug: etoricoxib; Drug: Diclofenac

Study type: Interventional

Funder types: Other

Identifiers

NCT01190722

201001HV

Details and patient eligibility

About

The investigators hypothesize that cyclooxygenas-II-selective inhibitors (Coxibs) provide a better patients assessed overall satisfaction when used for pain management after elective hallux valgus surgery as compared to traditional Non-steroidal anti-inflammatory drugs (NSAIDs).

Full description

The aim of the present study is to compare patients' satisfaction with pain medication during the first 7 first postoperative days following elective hallux valgus surgery in general anaesthesia between etoricoxib and diclofenac in a prospective randomised double-blind study design.

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiology (ASA) physiological class 1-2 patients
• aged 18-65 years
• scheduled for elective hallux valgus surgery in general anesthesia

Exclusion criteria

• NSAID allergy
• liver disease
• renal disease
• uncontrolled cardiovascular disease
• Lithium therapy
• chronic pain
• regular analgesia use

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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0 participants in 2 patient groups

etoricoxib

Experimental group

Description:

active study drug, coxib

Treatment:

Drug: etoricoxib

diclofenac

Active Comparator group

Description:

active traditional NSAID control

Treatment:

Drug: Diclofenac