A Study Evaluating The Absorption Of Varenicline Into The Body From A Varenicline Solution And A Varenicline Patch Applied To The Skin

Pfizer

Status and phase: Completed; Phase 1

Conditions: Smoking Cessation

Treatments: Drug: Varenicline free base solution; Drug: Varenicline free base patch

Study type: Interventional

Funder types: Industry

Identifiers

NCT00774605

A3051118

Details and patient eligibility

About

To evaluate the absorption, safety, and tolerability of a varenicline solution and a varenicline patch applied to the skin.

Full description

Additional Study Purpose Details: Evaluation of the pharmacokinetic profile of a varenicline solution and a varenicline patch applied to the skin

Enrollment: 12 patients

Sex: Male

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy, adult, male smokers

Exclusion criteria

• significant medical illness

Trial design

12 participants in 2 patient groups

Varenicline free base solution

Experimental group

Treatment:

Drug: Varenicline free base solution

Varenicline transdermal delivery system

Experimental group

Treatment:

Drug: Varenicline free base patch