A Study of Baked Milk Tolerance to Treat Eosinophilic Esophagtis

Mayo Clinic

Status: Completed

Conditions: Eosinophilic Esophagitis

Treatments: Dietary Supplement: Baked Milk

Study type: Interventional

Funder types: Other

Identifiers

NCT05606705

22-007941

Details and patient eligibility

About

This research is being done to see if patients with milk-triggered EoE are able to tolerate baked milk in their diet and if there is a threshold amount of straight milk that is tolerable.

Enrollment: 7 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with Eosinophilic esophagitis ≥ 15 eosinophils per HPF
• Going through or completed the six-food elimination diet, with milk only or milk plus one additional food identified as a trigger

Exclusion criteria

• Patients with conditions known to be associated with esophageal eosinophilia, including Crohn's disease, Churg-Strauss, achalasia, and hypereosinophilic syndrome
• Topical swallowed steroids within 8 weeks of study enrollment
• Inability to read due to: Blindness, cognitive dysfunction, or English language illiteracy

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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7 participants in 1 patient group

Baked Milk

Experimental group

Description:

Baked milk introduction into diet

Treatment:

Dietary Supplement: Baked Milk