A Study of Circulating Immune Cell Activity Changes in Blood of Colorectal Cancer Patients

Konkuk University Medical Center

Status: Completed

Conditions: Colorectal Cancer

Treatments: Device: Late stage; Device: Early stage

Study type: Observational

Funder types: Other

Identifiers

NCT02869269

KUH1160096

Details and patient eligibility

About

Previous studies have shown that colorectal cancer patients' prognosis and overall survival was related with immune cell expression in patients' tissue. However, the circulating immune cell activity changes in patients' blood has few studies. The purpose of this study is to analyze the variation of circulating immune cell activity in colorectal patients' blood which is classed as clinical staging.

Full description

The patients were classed as clinical staging

1. Early (stage1+2) and Late(stage3+4)
2. regional lymph node metastasis
3. Distant metastasis
4. TNM stage

Enrollment: 67 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient who was planned to undergo colorectal cancer surgery.

Exclusion criteria

• age < 20 years old
• history of hypersensitivity reaction in propofol or sevoflurane
• history of previous cancer
• patient with ongoing inflammation

Trial design

67 participants in 2 patient groups

Early stage

Description:

patients who diagnosed as TNM stage 1 and 2

Treatment:

Device: Early stage

Late stage

Description:

patients who diagnosed as TNM stage 3 and 4

Treatment:

Device: Late stage