A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD

Mayo Clinic

Status: Invitation-only

Conditions: Heart Failure With Preserved Ejection Fraction; Coronary Microvascular Dysfunction

Treatments: Diagnostic Test: Cardiovascular Magnetic Resonance (CMR)

Study type: Observational

Funder types: Other

Identifiers

NCT07093528

25-005812

Details and patient eligibility

About

To evaluate the effect of CS reducer implantation in patients with HFPEF and CMD on myocardial ischemia, measured by stress myocardial perfusion using cardiovascular magnetic resonance (CMR)

Enrollment: 25 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18
• Enrollment in main CS-reducer HFPEF study IRB# 25-002292

Exclusion criteria

• Metal implants that are not suitable for MRI
• Inability or unwillingness of individual to give written informed consent.

Trial design

25 participants in 1 patient group

Heart Failure with a Preserved Ejection Fraction (HFpEF)

Description:

Subjects with diagnosed Heart failure with a preserved ejection fraction (HFpEF), non-obstructive Coronary Artery Disease (CAD), and have documented CMD.

Treatment:

Diagnostic Test: Cardiovascular Magnetic Resonance (CMR)