A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

Mayo Clinic

Status: Enrolling

Conditions: LDL Hyper-responsiveness

Study type: Observational

Funder types: Other

Identifiers

NCT07137286

25-002523

Details and patient eligibility

About

The purpose of this study is to identify whether individuals following a ketogenic diet who experience extreme LDL-C elevation, termed "hyper-responders", have identifiable genetic variations in genes involved in cholesterol absorption.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age or older
• LDL-C >170 mg/dL in response to starting a ketogenic diet

Exclusion criteria

• Patients who do not consent to blood draw for genetic testing
• Those with LDL-C <170 mg/dL on a ketogenic diet